Nov 17, 2012

Growing concerns over 'in the air' transmission of Ebola

 


Ebola virus The infection is thought to get into humans through close contact with bodily fluids

Canadian scientists have shown that the deadliest form of the ebola virus could be transmitted by air between species.


In experiments, they demonstrated that the virus was transmitted from pigs to monkeys without any direct contact between them.

The researchers say they believe that limited airborne transmission might be contributing to the spread of the disease in some parts of Africa.

They are concerned that pigs might be a natural host for the lethal infection.

Start Quote

What we suspect is happening is large droplets - they can stay in the air, but not long, they don't go far. But they can be absorbed in the airway”
End Quote Dr Gary Kobinger Public Health Agency of Canada

Ebola viruses cause fatal haemorrhagic fevers in humans and many other species of non human primates.

Details of the research were published in the journal Scientific Reports.

According to the World Health Organization (WHO), the infection gets into humans through close contact with the blood, secretions, organs and other bodily fluids from a number of species including chimpanzees, gorillas and forest antelope.

The fruit bat has long been considered the natural reservoir of the infection. But a growing body of experimental evidence suggests that pigs, both wild and domestic, could be a hidden source of Ebola Zaire - the most deadly form of the virus.

Now, researchers from the Canadian Food Inspection Agency and the country's Public Health Agency have shown that pigs infected with this form of Ebola can pass the disease on to macaques without any direct contact between the species.

In their experiments, the pigs carrying the virus were housed in pens with the monkeys in close proximity but separated by a wire barrier. After eight days, some of the macaques were showing clinical signs typical of ebola and were euthanised.

One possibility is that the monkeys became infected by inhaling large aerosol droplets produced from the respiratory tracts of the pigs.

pigs could be a natural host Pigs could act as a host and amplify the Ebola virus

One of the scientists involved is Dr Gary Kobinger from the National Microbiology Laboratory at the Public Health Agency of Canada. He told BBC News this was the most likely route of the infection.

"What we suspect is happening is large droplets - they can stay in the air, but not long, they don't go far," he explained.

"But they can be absorbed in the airway and this is how the infection starts, and this is what we think, because we saw a lot of evidence in the lungs of the non-human primates that the virus got in that way."

The scientists say that their findings could explain why some pig farmers in the Philippines had antibodies in their system for the presence of a different version of the infection called Ebola Reston. The farmers had not been involved in slaughtering the pigs and had no known contact with contaminated tissues.

Read more at - http://www.bbc.co.uk/news/science-environment-20341423